产品货号：
JN2066
中文名称：
重组SARS-CoV-2 NSP1蛋白(His标签)
英文名称：
Recombinant SARS-CoV-2 Non-structural Protein 1 (C-6*His Tag)
产品规格：
10μg|50μg
发货周期：
1～3天
产品价格：
询价
本制品由E.coli表达系统制备，目的基因编码表达SARS-CoV-2 NSP1(Met1-Gly180)，C端包含一个6*His标签。
Accession#：YP_009725297.1
蛋白别名：SARS-CoV 2 nsp1;SARS-CoV 2 Leader protein
贮存液：20mM Tris-HCl,150mM NaCl,10% Glycerol,pH8.5（0.2μm过滤）
质量控制：
分子量：22.7kDa
实测分子量：25kDa（还原条件下）
纯度：＞85%（还原SDS-PAGE）
保存条件：-20℃，可稳定保存6个月，应避免反复冻融。
背景资料：
The Severe Acute Respiratory Syndrome (SARS) Coronavirus (CoV) is an enveloped,positive-stranded RNA viruses that can cause a severe respiratory disease.Its genome consists of a～30 kb linear,non-segmented,capped,polycistronic,polyadenylated RNA molecule,the first two-third of which is directly translated into two large polyproteins.These two polypeptides are processed into 16 non-structural proteins (nsps),forming the replicase complex,which is active in the cytoplasm in close association with cellular membranes.Nsp1 was proved to be able to suppress host gene expression by promoting host mRNA degradation and was involved in cellular chemokine deregulation.This virus evades the host innate immune response in part through the expression of its non-structural protein (nsp) 1,which inhibits both host gene expression and virus- and interferon (IFN)-dependent signaling.Thus,nsp1 is a promising target for drugs,as inhibition of nsp1 would make SARS-CoV more susceptible to the host antiviral defenses.
相关搜索：重组SARS-CoV-2 NSP1蛋白(His标签)，重组新型冠状病毒NSP1蛋白，重组新冠病毒NSP1蛋白，重组SARS-CoV-2非结构蛋白1
Accession#：YP_009725297.1
蛋白别名：SARS-CoV 2 nsp1;SARS-CoV 2 Leader protein
贮存液：20mM Tris-HCl,150mM NaCl,10% Glycerol,pH8.5（0.2μm过滤）
质量控制：
分子量：22.7kDa
实测分子量：25kDa（还原条件下）
纯度：＞85%（还原SDS-PAGE）
保存条件：-20℃，可稳定保存6个月，应避免反复冻融。
背景资料：
The Severe Acute Respiratory Syndrome (SARS) Coronavirus (CoV) is an enveloped,positive-stranded RNA viruses that can cause a severe respiratory disease.Its genome consists of a～30 kb linear,non-segmented,capped,polycistronic,polyadenylated RNA molecule,the first two-third of which is directly translated into two large polyproteins.These two polypeptides are processed into 16 non-structural proteins (nsps),forming the replicase complex,which is active in the cytoplasm in close association with cellular membranes.Nsp1 was proved to be able to suppress host gene expression by promoting host mRNA degradation and was involved in cellular chemokine deregulation.This virus evades the host innate immune response in part through the expression of its non-structural protein (nsp) 1,which inhibits both host gene expression and virus- and interferon (IFN)-dependent signaling.Thus,nsp1 is a promising target for drugs,as inhibition of nsp1 would make SARS-CoV more susceptible to the host antiviral defenses.
相关搜索：重组SARS-CoV-2 NSP1蛋白(His标签)，重组新型冠状病毒NSP1蛋白，重组新冠病毒NSP1蛋白，重组SARS-CoV-2非结构蛋白1